New Frontiers for Depression: Deep Brain Stimulation, Esketamine, and the Immune System

New Frontiers for Depression: Deep Brain Stimulation, Esketamine, and the Immune System

Drs. Mayberg, Murrough, and Nestler discuss their current research in developing personalized treatments for depression. Dr. Mayberg is a neurologist renowned for her study of brain circuits in depression and for her pioneering deep brain stimulation research, known as one of the first hypothesis-driven treatment strategies for a major mental illness. Dr. Murrough focuses on research into the variable disease pathways of depression, with the goal of differentiating subtypes of depressed patients and inventing new drugs that target these mechanisms. Dr. Nestler’s research uses animal models to delve into molecular mechanisms of depression, examining changes in gene expression and chromatin structure within the brain’s reward circuitry.


Published

September 23, 2019

Created by

Physician's Channel - Mount Sinai New York

Featured Faculty

Helen Mayberg, MD

Helen Mayberg, MD

Professor of Neurology, Neuroscience, Neurosurgery, and Psychiatry, Icahn School of Medicine at Mount Sinai; Director, The Nash Family Center for Advanced Circuit Therapeutics

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James Murrough, MD

James Murrough, MD

Associate Professor of Psychiatry and Neuroscience, Icahn School of Medicine at Mount Sinai; Director, Depression and Anxiety Center for Discovery and Treatment

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Eric Nestler, MD, PhD

Eric Nestler, MD, PhD

Dean for Academic and Scientific Affairs, Icahn School of Medicine at Mount Sinai; Director, The Friedman Brain Institute

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