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Surgical Transplantation of Human RPE Stem Cell-Derived RPE Monolayers into Non-Human Primates with Immunosuppression

OCT-A image processing procedure

Researchers at Icahn School of Medicine at Mount Sinai demonstrated that transplantation of RPE stem cells derived from human adult cadaver eyes and used to replace defective RPE is able to at least partially replace function in the macula of a non-human primate.

The research team co-lead by Timothy Blenkinsop, PhD, Assistant Professor of Cell, Developmental and Regenerative Biology and Ophthalmology, and member of the Black Family Stem Cell Institute and the Eye and Vision Research Institute at the Icahn School of Medicine at Mount Sinai, believes that the findings represent a major step forward in possible treatment of blinding retinal diseases such as macular degeneration.

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