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Mount Sinai Study Shows That Human Beliefs About Drugs Could Have Dose-Dependent Effects on the Brain


Mount Sinai researchers have shown for the first time that a person’s beliefs related to drugs can influence their own brain activity and behavioral responses in a way comparable to the dose-dependent effects of pharmacology.

The implications of the study, which directly focused on beliefs about nicotine, are profound. They range from elucidating how the neural mechanisms underlying beliefs may play a key role in addiction, to optimizing pharmacological and nonpharmacological treatments by leveraging the power of human beliefs. The study was published in the journal Nature Mental Health.

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