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Mount Sinai Researchers the First to Apply Single-Cell Analysis to Reveal Mechanisms of a Common Complication of Crohn’s Disease

Photo credit: Courtesy of Med/Cell Press (Elsevier)

Multimodal analyses of cells from abnormal tunnels in Crohn's disease converge to illuminate underlying

Study identifies key pathways underlying perianal fistula, a complication that is more prevalent and severe in African American populations.

Mount Sinai researchers have published the first study to use single-cell analysis in identifying several pathophysiological mechanisms of abnormal passageways in the digestive system known as perianal fistulae, a common complication of Crohn’s disease. These findings were published in the journal Med on April 24.

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