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First Stem Cells From a Bat Species Known to Harbor SARS-CoV-2 Could Shed Light on Virus Survival and Molecular Adaptability


Researchers from the Icahn School of Medicine at Mount Sinai have generated the first induced pluripotent stem cells (iPSCs) from bats, gaining valuable insights into the close relationship between bats and viruses. This research opens the door to studying how viruses like SARS-CoV-2, which causes COVID-19, survive, spread, and evade the immune system through molecular adaptations to new hosts.

The team’s findings, published February 21 in Cell, may also shed light on the unique properties of bats that underlie their remarkable defenses against aging and cancer.

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