Mount Sinai researchers demonstrated that small molecule DYRK1A inhibitors induce human beta cells to replicate by converting the repressive DREAM complex to its pro-proliferative MMB conformation—a crucial advance in the knowledge of this process.
Mount Sinai researchers demonstrated that small molecule DYRK1A inhibitors induce human beta cells to replicate by converting the repressive DREAM complex to its pro-proliferative MMB conformation—a crucial advance in the knowledge of this process.