Administration of Tranexamic Acid During Total Shoulder Arthroplasty Is Not Associated With Increased Risk of Complications in Patients With a History of Thrombotic Events
Tranexamic acid (TXA) has been shown to reduce blood loss and transfusion risk in various orthopedic surgeries including shoulder arthroplasty. However, concerns still exist regarding its use in patients with a history of thrombotic events. Using national claims data, this study examines the safety of TXA administration in shoulder arthroplasty patients with a history of thrombotic events. The study found that among shoulder arthroplasty patients, TXA use was not associated with increased complication odds, independent of a history of thrombotic events. These findings are in support of wider TXA use.