Infants born to mothers with IBD present with altered gut microbiome that transfers abnormalities of the adaptive immune system to germ-free mice
Researchers studied pregnant women with and without inflammatory bowel disease (IBD) to characterize the effect of maternal IBD on the priming of the early life gut microbiome in the offspring, which is critical for the proper development of the immune system.
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Professor of Genetics and Genomic Sciences
Mount Sinai Health System